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If it’s not broke, should we FiX it?

Drs. Panos and Peksa

Nick Panos, PharmD
Clinical Lead, Critical Care
Clinical Pharmacy Specialist, Neurosciences ICU
Rush University Medical Center, Chicago, IL

Gary D. Peksa, PharmD, MBA, BCPS
Manager, Clinical Pharmacy
Assistant Professor, Emergency Medicine
Rush University Medical Center, Chicago, IL

A Knowledge-Based Activity
ACPE UAN: 0016-0000-22-029-L01-P, 1.0 contact hour (0.1 CEUs)
1.0 AMA PRA Category 1 Credit(s)™ CME
1.0 contact hour CNE

Learning Objectives:

  • Describe the mechanisms of action of prothrombin complex concentrates and identify which components are beneficial in the treatment of hemorrhage due to anticoagulation
  • Summarize current evidence supporting the use of fixed-dose versus variable-dose prothrombin complex concentrate regimens in anticoagulation reversal
  • Explain whether present literature affirms a fixed-dose prothrombin complex concentrate regimen confers a safety benefit over a variable-dose regimen

Speaker Disclosures

All speakers, planning committee members, and reviewers who contributed to this activity have no relevant financial relationships with ineligible companies to disclose.